Augmentation of retrovirus-induced lymphoid leukosis by Marek's disease herpesviruses in White Leghorn chickens.

Response of white leghorn chickens of various genetic lines to infection with avian leukosis virus subgroup J.

In Experiment 1, chickens from various white leghorn experimental lines were inoculated with strain ADOL-Hcl of subgroup J avian leukosis virus (ALV-J) either as embryos or at 1 day of age. At various ages, chickens were tested for ALV-J induced viremia, antibody, and packed cell volume (PCV). Also, at 4 and 10 wk of age, bursal tissues were examined for avian leukosis virus (ALV)-induced prene...

Susceptibility of various parental lines of commercial white leghorn layers to infection with a naturally occurring recombinant avian leukosis virus containing subgroup B envelope and subgroup J long terminal repeat.

Chickens from seven different parental lines of commercial White Leghorn layer flocks from three independent breeders were inoculated with a naturally occurring avian leukosis virus (ALV) containing an ALV-B envelope and an ALV-J long terminal repeat (LTR) termed ALV-B/J. Additional groups of chickens from the same seven parental lines were inoculated with ALV-B. Chickens were tested for ALV vi...

Effect of selection for resistance and susceptibility to viral diseases on concentrations of dopamine and immunological parameters in six-week-old chickens.

White Leghorn chickens were inbred respectively from their parent lines, which were diversely selected for resistance (line 6(3)) or susceptibility (lines 7(2) and 15I(5)) to Marek's disease and lymphoid leukosis. The differences in disease resistance may have been due to differential regulation of immune and neuroendocrine homeostasis. At 5 wk of age, chickens from the same line were randomly ...

Pathologic differentiation between lymphoid leukosis and Marek's disease in chickens: light and electron microscopic observations.

Replication of Marek's disease virus in cell cultures derived from genetically resistant chickens.

Various parameters of replication of Marek's disease virus (MDV) were studied in cells derived from genetically resistant (line 6) and susceptible (line 7) chickens. Cell-free and cell-associated preparations of three strains of pathogenic MDV (JM, GA, and Id-1) replicated equally well in cells of resistant and susceptible chickens. There were no demonstrable differences between the two genetic...